Description
Product Characteristics:
Binds to type I and II regulatory subunits of protein kinase A and anchors them to the cytoplasmic face of the mitochondrial outer membrane.
Subcellular location: Cytoplasm
Synonyms: AKAP, PRKA1, AKAP84, TDRD17, AKAP121, AKAP149, D-AKAP1, PPP1R43, SAKAP84, A-kinase anchor protein 1, mitochondrial, A-kinase anchor protein 149 kDa, AKAP 149, Dual specificity A-kinase-anchoring protein 1, D-AKAP-1, Protein kinase A-anchoring protein 1, Spermatid A-kinase anchor protein 84, S-AKAP84, AKAP1
Target Information: The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein binds to type I and type II regulatory subunits of PKA and anchors them to the mitochondrion. This protein is speculated to be involved in the cAMP-dependent signal transduction pathway and in directing RNA to a specific cellular compartment. [provided by RefSeq, Jul 2008]